Lower risk of dementia in AF patients treated with oral anticoagulation

15-11-2017 • Friberg L et al., Eur Heart J 2017
In a large retrospective cohort study, the risk of dementia was higher without oral anticoagulant treatment in patients with AF, compared with AF patients receiving oral anticoagulation. Read more
News • 14-11-2017

In the SPRINT trial, presence or absence of staff did not affect observed CVD risk reduction

AHA 2017 A post-hoc survey of the SPRINT examined whether the presence or absence of physician or nursing in the BP measurement changed the treatment effect. Read more

Omega-3 carboxylic acids can benefit patients with severe hypertriglyceridemia

13-11-2017 • Stroes ESG et al., J Clin Lipidol 2017
Patients with SHTG treated with OM3-CA 2 g daily had a statistically significant reduction in TG and non-HDL-c concentrations compared with those treated with olive oil 2 g daily. Read more

Rationale and effect of targeting IL-1beta to lower inflammation and thereby CV events

31-10-2017 • Libby P. J Am Coll Cardiol. 2017
This review summarizes the rationale to specifically target IL-1beta to lower residual inflammatory risk, now shown to be effective in the CANTOS trial. Other potential targets are also discussed. Read more
E-Learning •

Things to consider when aiming to prevent stroke in a patient with AF

EPCCS 2017 Prof. David Fitzmaurice and dr. Geert-Jan Geersing consider the updates in the latest ESC Guidelines on atrial fibrillation that are most relevant to GPs, including which risk scores can help to optimally manage AF, and which drawbacks the scores have. Read more

Lipid parameters vary depending on age and sex

16-10-2017 • Balder JW et al., J Clin Lipidol. 2017
Based on data of the large Dutch Lifelines cohort, reference values have been developed for lipid parameters. Read more
News • 14-11-2017

New ACC/AHA Hypertension Practice Guidelines stress lifestyle improvement and lower SBP target

AHA 2017 The new guidelines now define hypertension as >130/80 mmHg, emphasize the need for lifestyle changes and specify details of accurate BP measurement methods.  Read more
News • 13-11-2017

CV benefit seen in CANTOS trial explained by response to anti-inflammatory treatment

AHA 2017 A new analysis of CANTOS data shows that patients who achieved hsCRP <2 mg/L benefitted from a 25% reduction in MACE, irrespective of the dose of canakinumab. Read more

Cognitive dysfunction in diabetic patients partly explained by hyperglycemia

1-11-2017 • Geijselaers SLC et al., Diabetes Care 2017
Differences in cognitive performance between diabetic patients and individuals with normal glucose levels can be explained by hyperglycemia and by BP-related variables, but not by insulin resistance. Read more

Early lipid changes ≥5% during psychotropic therapy as a warning sign of future clinically relevant dyslipidemia

30-10-2017 • Delacrétaz A et al., J Clin Lipidol 2017
These data underscore the importance of prospectively monitoring lipid parameters in all patients starting psychotropic treatment, as these drugs may induce or exacerbate dyslipidemia. Read more

Hypertension in midlife associated with higher risk of dementia in women

18-10-2017 • Gilsanz P et al., Neurology 2017
Although midlife hypertension is more common in men, it was only associated with the risk of dementia in women, suggesting that hypertension is a modifiable risk factor for dementia in women. Read more

More adverse events with generic ARBs compared with branded ARBs

13-10-2017 • Leclerc J et al., Circ Cardiovasc Qual Outcomes 2017
The use of generic ARBs resulted in higher rates of hospitalizations and emergency room consultations, particularly in the first month and with candesartan. Read more

Upcoming meetings

Meeting reports & resources

EPCCS 2017 Report of the Cardiovascular Summit held in Dublin, Ireland
EPCCS Guidance Documents Evidence- and meeting-based guidance for primary care
EPCCS 2015 Report of 8th Annual EPCCS meeting held in Prague.
EPCCS 2014 Report of 7th Annual EPCCS meeting held in Brussels.
All meeting reports...