Addition of ezetimibe to statin therapy does not affect glucose metabolism

12-4-2016 • Barkas F et al., J Clin Lipid 2016
High-intensity statin treatment in prediabetics is associated with an increased risk of incident diabetes but the addition of ezetimibe to statin had a neutral effect on glucose metabolism. Read more

Substantial variability in response to statin treatment

6-4-2016 • Karlson BW, et al. Eur Heart J Cardiovasc Pharmacother
There is considerable individual variation in LDL-C reduction at all doses of simvastatin, atorvastatin and rosuvastatin, which is important to consider in daily clinical practice. Read more
News • 29-3-2016

Chest pain reported by men and women with suspected heart disease, but formulated differently

Gender analyses of the PROMISE trial showed that chest pain and shortness of breath were the main symptoms in both men and women in suspected stable CAD, but the description of chest pain differs between the sexes. Read more

Diabetic patients with SBP < 140 mmHg may be harmed by BP-lowering treatment

16-3-2016 • Brunström M et al., BMJ 2016
Large systematic review and meta-analysis shows that antihypertensive treatment provides no benefit and increases the risk of CV death in diabetic patients with SBP<140 mm Hg. Read more

Differential importance of risk factors for various CV disease manifestations

14-3-2016 • Stoekenbroek RM et al., Eur Heart J 2016
In a large cohort study, the strength of associations between LDL-C, SBP, smoking and CVD manifestations occurring in various vascular beds was highly variable. Read more

LDL-c levels of adult children associated with maternal LDL-c levels before pregnancy

9-3-2016 • Mendelson MM et al., JAMA Cardiol 2016
Dyslipidaemia in young adults may affect lipid levels of their offspring, possibly through epigenetic mechanism. More insight in these processes may yield population-based lifestyle strategies. Read more

Morning home BP measurement better predicts CAD events than clinic BP

12-4-2016 • Kario K et al., J Am Coll Cardiol. 2016
Morning home BP measurements were strong predictors of both CAD risk and stroke in HONEST study. Clinic SBP and evening SBP may underestimate risk, as well as diastolic BP in either setting. Read more

Response to statin therapy is directly related to CVD incidence

30-3-2016 • Ridker PM, et al. Eur Heart J 2016
The magnitude of the percentages reduction in LDL-C, non-HDL-C, and apoB following statin therapy is highly variable between individuals, and is directly related to the reduction in CV risk. Read more

High blood pressure can effectively be controlled with some diets

17-3-2016 • Gay HC et al., Hypertension. 2016
A large meta-analysis shows that dietary interventions lead to clinically significant net BP reductions, but effects vary between types of diet, and within different patient subgroups. Read more
E-Learning •

What is the evidence base for lipid modification in the guidelines updates?

Richard Hobbs (Oxford, UK) and Arno Hoes (Utrecht, The Netherlands) summarise the lively discussion after Hoes' talk on dilemmas in lipid-lowering in primary care. Read more
News • 14-3-2016

Patients with atrial fibrillation can benefit from yoga

A randomised trial in patients with paroxysmal atrial fibrillation, shows that yoga improves quality of life, when practised in addition to standard medical treatment. Heart rate and blood pressure also decreased in patients who did yoga. Read more

Immediately after moderate and heavy alcohol consumption acute CV risk is increased

8-3-2016 • Mostofsky E et al., Circulation 2016
Moderate alcohol consumption was associated with a higher CV risk in the hour after alcohol intake, and a lower CV risk after 24 hours, while heavy drinking yields continuous CV risk. Read more

Upcoming meetings

Meeting reports & resources

EPCCS 2017 Report of the Cardiovascular Summit held in Dublin, Ireland
EPCCS Guidance Documents Evidence- and meeting-based guidance for primary care
EPCCS 2015 Report of 8th Annual EPCCS meeting held in Prague.
EPCCS 2014 Report of 7th Annual EPCCS meeting held in Brussels.
All meeting reports...