News • 1-7-2017

EPCCS Heart Failure Guidance published as Clinical Intelligence in Br J Gen Prac

A brief version of our EPCCS Practical Guidance on Heart Failure Diagnosis and Management in Primary Care has now been published as Clinical Intelligence paper in the British Journal of General Practice. Read more

Adequate effectivity long-acting statins with morning intake

27-6-2017 • Awad K, et al. J Clin lipidol, 2017
Short-acting statins are significantly more effective in lowering LDL-C and total cholesterol when taken in the evening, but long-acting statins are equally effective when taken in the morning or evening. Read more

CV risk factors early in life associated with worse midlife cognitive performance

21-6-2017 • Rovio SP et al, JACC 2017
In a population-based cohort, the cumulative burden of BP, serum total- and LDL-C, and smoking from childhood and adolescence, were independently associated with worse midlife cognitive performance. Read more

Tooth brushing at least twice a day for 2 min or more associated with better endothelial function

19-6-2017 • Matsui S et al., Int J Cardiol 2017
High frequency and long duration of tooth brushing were associated with a better endothelial function, implying that adequate tooth brushing may contribute to the prevention of CV events. Read more

In children with heterozygous FH, progression of carotid atherosclerosis slowed by statin treatment

13-6-2017 • Braamskamp MJAM et al., Circulation 2017
Children with heterozygous FH treated with rosuvastatin showed lower progression of carotid atherosclerosis as compared with unaffected und untreated siblings Read more

Long-term metformin seems to protect against coronary atherosclerosis in prediabetic men

8-6-2017 • Goldberg RB et al., Circulation 2017
In a large Diabetes Prevention Program, men with prediabetes treated with metformin for an average duration of 14 years had lower coronary calcium scores compared with the placebo group. Read more

Reaching lower than recommended dose ACEi/ARBs or beta-blockers associates with lower survival chance

28-6-2017 • Ouwerkerk W, et al, Eur Heart J, 2017
In the BIOSTAT-CHF study, reaching less than 50% of the ESC guideline recommended dose of ACE-inhibitor/ARB or beta-blocker doses was associated with worse survival in HF patients.  Read more
E-Learning •

How do the latest guideline changes affect management of dyslipidaemia in primary care?

EPCCS 2017 Dr. Frans Rutten and dr. Carlos Brotons summarise the latest updates in the ESC guidelines on dyslipidaemia, relevant for the GP, and summarise the discussion this presentation sparked among the EPCCS audience. Read more

NOACs confer lower bleeding risk than VKA in low-risk AF patients

21-6-2017 • Lip GYH et al., JAMA Cardiol. 2017
In AF patients with a single non-gender-related stroke risk factor, the risk of any bleeding was lower for apixaban and dabigatran compared with warfarin, while no difference in stroke prevention was seen. Read more

Certain traditional Chinese medicines may help improve CV risk or even CVD

14-6-2017 • Hao P et al., JACC 2017
Systematic review of RCT evidence suggests that some TCM medications might improve CV risk factors and some may exert beneficial effects on ASCVD and chronic HF. Not all studies are of high methodological quality. Read more

Risk stratification in diabetic patients can be improved by considering SBP variability

8-6-2017 • Ohkuma T et al., Hypertension 2017
In diabetic patients, the SBP visit-to-visit variability was an independent predictor of vascular complications and death, and improved the predictive ability of traditional risk factors. Read more

Meta-analyses confirms CVD and all-cause mortality benefit of intensive SBP reduction

7-6-2017 • Bundy JD et al., JAMA Cardiol. 2017
A large meta-analysis demonstrated that treating patients to reduce SBP below currently recommended targets was associated with a significantly reduced risk of CVD and all-cause mortality. Read more

Upcoming meetings

Meeting reports & resources

EPCCS 2017 Report of the Cardiovascular Summit held in Dublin, Ireland
EPCCS Guidance Documents Evidence- and meeting-based guidance for primary care
EPCCS 2015 Report of 8th Annual EPCCS meeting held in Prague.
EPCCS 2014 Report of 7th Annual EPCCS meeting held in Brussels.
All meeting reports...