Selected literature
Mallaina P, Lionis C, Rol H, et al.
CV-ASPIRE confirms that smoking is a significant predictor of long-term CV events thus underscores the importance of addressing this modifiable risk factor
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Selected literature
Schuler G, Adams V, Goto Y.
We summarise the molecular consequences of exercise and strategies to increase compliance to frequent exercise.
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Selected literature
JACC, March 2013. Exposure to second-hand tobacco smoke is a risk factor for coronary artery calcification, at least as strong as other well-established risk factors.
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Selected literature
Lancet, february 2013. Calcium-channel blocker-based therapy gives more protection to non-obese patients than does diuretic-based therapy, whereas both regimes are effective in obese patients.
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Selected literature
Eur J Prev Cardiol. 2013 Statins reduce all-cause mortality and major coronary events both in patients with cardiovascular disease and in high-risk individuals without disease.
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Selected Literature
NEJM Feb 2013, Suggested protective effect of Mediterranean diet on cardiovascular disease now confirmed in randomised trial.
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Selected Literature
Vernooij J W P et al. BMJ 2012;344:bmj.e3750
Patients with vascular disease are at higher risk of suffering a further event or death. Treatment of vascular risk factors by nurse practitioners is proven to be very effective in reducing this risk. This study looks at one year effect in a relatively large group of patients. The primary end point of the study was the relative change in Framingham risk score (FRS) after one year.
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Selected literature
Cullington D, Goode KM, Clark AL, Cleland JG. Eur J Heart Fail. 2012 May 22.
Heart rate reduction is important to decrease the risk of cardiovascular events and improve prognosis. This study evaluated whether beta-blocker dose or heart rate was more strongly associated with mortality in patients with stable chronic heart failure.
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Selected Literature
Diabetes Care. 2012 Apr 19
The American Diabetes Association and the European Association for the Study of Diabetes have updated guidelines on the management of hyperglycemia in nonpregnant adults with type 2 diabetes. Individualized treatment is the cornerstone of success
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It is unclear whether angiotensin-converting enzyme inhibitors (ACE-I) or angiotensin receptor blockers (ARB) are beneficial in individuals with, or at increased risk for, atherosclerotic vascular disease who are normotensive. This study attempted to answer this question. McAlister FA, Eur Heart J. 2011 Oct 31. [Epub ahead of print]
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A long-term follow-up of the ALLHAT shows that hypertension control to prevent heart failure can be achieved in most patients; diuretics can be an effective part of the antihypertensive treatment regimen. Circulation. 2011;124:1811-1818
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Heart failure occurs when the ventricles have a reduced ability to fill or to eject blood, resulting in an insufficient cardiac output to satisfy the metabolic needs of the body. There is a common perception that heart failure is a disease of the elderly, which has a slow onset in primary care and is always left sided.
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Diabetes is a growing epidemic and it is estimated that by 2050, 1 in 3 Americans will have the condition. However, hypoglycaemia is a major issue in both Type 1 and Type 2 diabetics.
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Ambulatory blood pressure monitoring is more accurate than both clinic and home monitoring in diagnosing hypertension. This study compared the cost-effectiveness of different diagnostic strategies for hypertension. Lancet. 2011 Oct 1;378(9798):1219-30.
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Effect of intensive glucose lowering treatment on all cause mortality, CV death, and microvascular events in type 2 diabetes
Glucose lowering treatments are widely used to treat type 2 diabetes ant to prevent long term cardiovascular complications as well as impairment of renal and visual functions. This meta-analysis aimed to determine the benefit of such treatment on clinical end points. BMJ. 2011 Jul 26;343:d4169. doi: 10.1136/bmj.d4169
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Excess risk attributable to traditional cardiovascular risk factors in clinical practice settings across Europe
The objective of this study was to estimate the excess risk attributable, firstly, to the presence of CVD risk factors and, secondly, to the lack of control of these risk factors in primary prevention care across Europe. BMC Public Health. 2011 Sep 18
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The recent updated guidance from the National Institute for Health and Clinical Excellence (NICE) on the management of hypertension in adults will have far reaching implications for day to day practice in the United Kingdom.
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Recent increases in obesity, diabetes, and hypertension, along with the aging of the population, are driving a dramatic rise in the prevalence of chronic kidney disease (CKD). Primary care practices are at the forefront of detection and management of early CKD.
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Family practice survey which identifies key factors for improvinh risk reduction in combination hypertension + T2DM - FREE PUBLICATION ATTACHED
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A cost study in family practices - FREE PUBLICATION ATTACHED
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Prevalence of target organ damage in hypertensive subjects attending primary care
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Diabetes screening and early intensive intervention in general practice - SLIDES ATTACHED
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