Consensus guidance on management of statin-associated muscle symptoms (SAMS)
19-2-2015 • Stroes ES et al., Eur Heart J 2015
EAS Consensus Panel reviews what is known about mechanism of statin-induced myopathy and gives recommendations to ensure optimal LDL-lowering therapy in patients experiencing SAMS.
Lowering BP beyond guideline recommendations may be beneficial in type 2 diabetes
11-2-2015 • Emdin CA et al., JAMA. 2015
Meta-analysis suggests that lowering blood pressure beyond the often recommended systolic BP of 140 mmHg, to below 130 mmHg may reduce the risk of stroke, retinopathy and albuminuria.
Adverse perinatal outcomes not different between tight or less-tight BP control during pregnancy
5-2-2015 • Magee LA et al., NEJM 2015
Randomised trial shows that risk of adverse perinatal outcomes or serious maternal complications does not differ between tight or less-tight control of maternal hypertension.
Incidence of major bleedings with rivaroxaban in real world similar to trial setting
28-1-2015 • Tamayo S et al., Clin Cardiol 2015
The incidence of major bleeding in patients with NVAF taking rivaroxaban in standard clinical practice was similar to randomised trials. Most bleedings were of gastrointestinal or intracranial origin and fatal bleedings were rare.
News • 26-1-2015
Positive opinion of EMA for use of liraglutide for weight management in obesity
Based on clinical trial data, a positive opinion is adopted for use of the GLP-1 analogue in addition to adequate diet and physical activity, for weight management in obesity.
Cognitive dysfunction predicted by variation in blood pressure and high heart rate
20-1-2015 • Böhm M et al., Hypertension 2014
In patients with high CV risk, visit-to-visit variation in systolic blood pressure and high resting heart rate were independent predictors of cognitive decline, dysfunction and deterioration.
Webcast • Amsterdam
Stroke prevention in atrial fibrillation
Four European Primary Care experts, prof. Richard Hobbs, prof. David Fitzmaurice, Clare Taylor MD and Frans Rutten MD, summarise a fascinating discussion at the stroke prevention in atrial fibrillation expert meeting.
LDL-c lowering effect lower when switching from high-efficacy to generic lipid-lowering therapy
9-2-2015 • Cao et al., Clin Ther. 2015
In high-risk CVD patients, an increase of LDL-c and lower LDL-c goal attainment rates were seen when patients switched from simvastatin/ezetimibe or rosuvastatin to simvastatin monotherapy.
More longevity benefit with light than with intensive jogging
2-2-2015 • Schnohr et al., JACC 2015
A U-shaped relationship was found between jogging and mortality, with the lowest mortality seen among light joggers (1-2.4 hours per week, maximum 3 days per week, at a slow or average pace).
Glycaemic control in T2DM patients with renal failure may improve with DPP4-inhibitor
27-1-2015 • Laakso et al., Diabetes Care 2015
In patients with type 2 diabetes and moderate to severe renal impairment, the DPP4-inhibitor linagliptide lowered HbA1c , with an acceptable side-effect profile and without affecting eGFR.
Biomarker as a guide in choosing the optimal treatment for smoking cessation
24-1-2015 • Lerman C et al., Lancet Respir Med 2015
Treating normal nicotine metabolisers with varenicline and slow metabolisers with nicotine patch could optimise quit rates while minimising side-effects.
Self-reported memory complaints in highly educated individuals indicates higher risk of stroke
12-1-2015 • Sajjad A et al., 2015
Individuals with subjective memory complaints, especially those with a high level of education, showed a higher risk of stroke than those who did not report memory complaints.
EPCCS 8th Annual Scientific Meeting
September 17-18, 2015 , Prague, Czech Republic
20th WONCA Europe Conference
22 - 25 oktober 2015, Istanbul, Turkey
All upcoming meetings...
Meeting reports & resources
Report of 7th Annual EPCCS meeting held in Brussels.
Report of 6th Annual EPCCS meeting held in London
Report of 5th Annual EPCCS meeting held in Athens
Report of 4th Annual EPCCS meeting held in Berlin
All meeting reports...