News • 15-9-2017

Risk factor management insufficient in transgender patients with diabetes

EASD 2017 Despite management by a multidisciplinary team, transgender persons with diabetes treated with hormones for gender confirmation had modifiable risk factors that aggravate diabetes. Read more

Statin treatment effective in pediatric patients with homozygous FH

13-9-2017 • Stein EA et al. J Am Coll Cardiol. 2017
In children and adolescents with HoFH, rosuvastatin 20 mg alone or in combination with ezetimibe and/or apheresis led to an effective LDL-C reduction, and was well tolerated. Read more
News • 10-9-2017

‘The lower the better’ even holds at very low achieved LDL-c

ESC 2017 FOURIER trial data show that after 2.2 years of follow-up, very low LDL-c levels are still associated with further reduction of CV events, without an increase in safety events. Read more
News • 10-9-2017

Reducing inflammation lowers CV events and possibly lung cancer rates

ESC 2017 Inhibition of IL-1β with canakinumab significantly lowered hsCRP levels and CV events, especially in those with higher than median CRP reduction, and incident lung cancer and lung cancer mortality were reduced. Read more
News • 9-9-2017

Early risk factor-driven upstream therapy can prevention of progression atrial fibrillation

ESC 2017 Data from the RACE 3 trial showed effective, feasible and safe risk factor-driven upstream therapy compared to conventional therapy for maintaining sinus rhythm in atrial fibrillation. Read more

Early statin discontinuation associated with higher risk of recurrent stroke

23-8-2017 • Lee M et al., J Am Heart Assoc. 2017;6:e005658
The discontinuation of statin therapy 3 to 6 months after an index ischemic stroke event, was associated with a higher risk of recurrent stroke within 1 year after statin discontinuation. Read more
News • 15-9-2017

New NHS device to help loose weight and improve glucose regulation in obese T2DM patients

EASD 2017 NHS provides the new, non-surgical, reversible weight loss Endobarrier device to help patients with poorly controlled T2DM and obesity kickstart a change in lifestyle. Read more
E-Learning •

What can be learned from the latest hypertension trials?

EPCCS 2017 Prof. Richard McManus summarises the results of three large trials that evaluated different intensities of blood pressure management and different blood pressure targets. With prof. Richard Hobbs, he considers what lessons can be learned for primary care. Read more
News • 10-9-2017

ESC GRAND DEBATE | Inflammation and cardiovascular disease

ESC 2017 One of the Grand Debates focused on different interpretations of the CANTOS trial data. Paul Ridker and Alberico Catapano debated how central inflammation is to CVD. Read more
News • 9-9-2017

In patients with very high BP, intensive blood pressure lowering can be harmful

ESC 2017 Posthoc SPRINT analysis shows that persons with SBP ≥160 mmHg and low Framingham risk score, have a higher risk of all-cause mortality with intensive treatment. Read more

Patients with cerebrovascular disease benefit from BMI 27-28 kg/m2 and little abdominal obesity

24-8-2017 • Jaspers NEM, et al. Int J Obes 2017
In clinically stable patients with cerebrovascular disease, the lowest risk of mortality and morbidity was associated with a BMI of 27-28 kg/m2, combined with little abdominal obesity. Read more

More than 3.7 g sodium per day has a negative effect on cardiac mechanics

22-8-2017 • Selvaraj S, et al, JACC 2017
Daily sodium intake of more than 3.7 g is associated with abnormal cardiac mechanics, and this relationship is only partially mediated by systolic blood pressure and serum aldosterone levels. Read more

Upcoming meetings

Meeting reports & resources

EPCCS 2017 Report of the Cardiovascular Summit held in Dublin, Ireland
EPCCS Guidance Documents Evidence- and meeting-based guidance for primary care
EPCCS 2015 Report of 8th Annual EPCCS meeting held in Prague.
EPCCS 2014 Report of 7th Annual EPCCS meeting held in Brussels.
All meeting reports...